Description

8-Chloro-2H-chromene-3-carbonitrile is a versatile and high-value chromene derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular scaffold, featuring a chloro-substituted chromene ring fused with a nitrile group, makes it an essential building block for constructing complex heterocyclic compounds. This product is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Serves as a monomer or precursor for the synthesis of specialty polymers and organic electronic materials.
• Chemical Synthesis: An important building block for constructing complex fused-ring systems and other chromene derivatives in academic and industrial research.
• Dye & Pigment Intermediate: Utilized in the development of novel chromophores and functional dyes due to its conjugated system.

Basic Information

Product Name	8-Chloro-2H-chromene-3-carbonitrile
CAS No.	885270-78-0
Molecular Formula	C10H6ClNO
Molecular Weight	191.61 g/mol
Synonyms	8-Chloro-2H-1-benzopyran-3-carbonitrile; 8-Chloro-3-cyano-2H-chromene; 8-Chloro-3-cyano-2H-1-benzopyran; 2H-1-Benzopyran-3-carbonitrile, 8-chloro-; 885270-78-0
EINECS	Contact for details

Quality Control

Our 8-Chloro-2H-chromene-3-carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our commitment to reliable supply and batch-to-batch consistency supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or using amber glass containers where prolonged exposure is expected.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.