Description

tert-Butyl(4-Aminotetrahydro-2H-Pyran-4-Yl)Methylcarbamate is a specialized Boc-protected amino piperidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a protected amine functionality and a rigid tetrahydropyran scaffold, enabling the construction of complex molecules with precise stereochemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The Boc-protected amine and cyclic ether structure make it valuable for creating peptide analogs and mimetics in medicinal chemistry.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A high-value starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	tert-Butyl(4-Aminotetrahydro-2H-Pyran-4-Yl)Methylcarbamate
CAS No.	885269-69-2
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	tert-Butyl N-[(4-Aminotetrahydro-2H-pyran-4-yl)methyl]carbamate; 4-(Aminomethyl)-4-piperidinol, 1-Boc derivative; 1-Boc-4-(aminomethyl)-4-hydroxypiperidine; 4-(Boc-aminomethyl)-4-hydroxypiperidine; 4-(Aminomethyl)-4-hydroxypiperidine-1-carboxylic acid tert-butyl ester; 4-(Aminomethyl)-4-piperidinol, N-Boc derivative; tert-Butyl (4-amino-4-(hydroxymethyl)piperidin-1-yl)carboxylate (tautomeric form); BOC-4-Aminomethyl-4-hydroxypiperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl(4-Aminotetrahydro-2H-Pyran-4-Yl)Methylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.