Description

4-Amino-6-Chloro-2-Methylchroman-4-Carboxylic Acid is a high-purity, synthetically versatile chroman derivative. This compound serves as a critical pharmaceutical intermediate and building block in advanced organic synthesis. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Fine Chemical Synthesis: Used in the preparation of complex chroman-based molecules for material science and specialty chemistry applications.
• Academic & Contract Research: Valuable reagent for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.
• Process Chemistry: Serves as a starting material or intermediate in scalable, GMP-compliant manufacturing processes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Amino-6-Chloro-2-Methylchroman-4-Carboxylic Acid
CAS No.	885269-58-9
Molecular Formula	C11H12ClNO3
Molecular Weight	241.67 g/mol
Synonyms	4-Amino-6-chloro-2-methyl-4-chromancarboxylic acid; 4-Chromanecarboxylic acid, 4-amino-6-chloro-2-methyl-; 6-Chloro-4-amino-2-methylchroman-4-carboxylic acid; 2-Methyl-6-chloro-4-aminotetrahydro-4H-1-benzopyran-4-carboxylic acid; 4-Amino-6-chloro-2-methyl-3,4-dihydro-2H-1-benzopyran-4-carboxylic acid; 4-Carboxy-4-amino-6-chloro-2-methylchroman
EINECS	Contact for details

Quality Control

Our 4-Amino-6-Chloro-2-Methylchroman-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.