Description

1-([(2,3,5,6-Tetramethylphenyl)Sulfonyl]Amino)Cyclohexanecarboxylic Acid CAS NO 885269-54-5 is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonamide-linked cyclohexane and tetramethylphenyl structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories, agrochemical manufacturers, and specialty chemical producers for creating new compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in areas requiring sulfonamide-based pharmacophores.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the synthesis of compound libraries for high-throughput screening.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, or plant growth regulators that incorporate sulfonamide functionalities.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex molecules due to its reactive amino and carboxylic acid groups.
• Protease Inhibitor Development: Potential application in the design and synthesis of enzyme inhibitors where the sulfonamide group acts as a bioisostere.
• Material Science Precursor: Can be utilized in the synthesis of specialized polymers or ligands for catalytic systems.

Basic Information

Item	Information
Product Name	1-([(2,3,5,6-Tetramethylphenyl)Sulfonyl]Amino)Cyclohexanecarboxylic Acid
CAS No.	885269-54-5
Molecular Formula	C19H27NO4S
Molecular Weight	365.49 g/mol
Synonyms	1-[(2,3,5,6-Tetramethylbenzenesulfonyl)amino]cyclohexane-1-carboxylic acid; N-(2,3,5,6-Tetramethylphenylsulfonyl)-1-aminocyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 1-[[(2,3,5,6-tetramethylphenyl)sulfonyl]amino]-; 1-Amino-N-(2,3,5,6-tetramethylphenylsulfonyl)cyclohexanecarboxamide (tautomeric form); TMPSA-CHA; Tetramethylphenyl sulfonyl amino cyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-([(2,3,5,6-Tetramethylphenyl)Sulfonyl]Amino)Cyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure compliance with research and development grade standards. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.