Description

4-Iodo-2,2-Dimethyl-Tetrahydro-Pyran is a valuable halogenated heterocyclic building block, specifically an iodinated tetrahydropyran derivative. This compound is engineered to provide a reactive iodine handle and a protected oxygen functionality, making it a critical intermediate for advanced organic synthesis. It is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where the iodotetrahydropyran moiety is incorporated.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific optical or electronic properties.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags for studying biological systems.

Basic Information

Product Name	4-Iodo-2,2-Dimethyl-Tetrahydro-Pyran
CAS No.	882687-80-1
Molecular Formula	C7H13IO
Molecular Weight	240.08 g/mol
Synonyms	4-Iodo-2,2-dimethyltetrahydropyran; 2,2-Dimethyl-4-iodotetrahydropyran; 4-Iodo-2,2-dimethyloxane; Tetrahydro-4-iodo-2,2-dimethyl-2H-pyran; 882687-80-1
EINECS	Contact for details

Quality Control

Our 4-Iodo-2,2-Dimethyl-Tetrahydro-Pyran is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.