Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-1-[(4-Methylphenyl)Sulfonyl]-2-(Tributylstannyl)- is a high-value organotin intermediate critical for advanced pharmaceutical synthesis and materials science research. This compound is specifically engineered for use in Stille cross-coupling reactions, enabling the efficient formation of carbon-carbon bonds under mild conditions. It is an essential building block for medicinal chemists and R&D laboratories developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex heterocyclic compounds for oncology, antiviral, and central nervous system (CNS) drug candidates.
• Stille Cross-Coupling Reagent: Facilitates the coupling of sp2-hybridized carbon atoms, crucial for constructing conjugated systems in drug discovery and material science.
• Agrochemical Research: Used in developing novel pesticides and herbicides with enhanced efficacy and selectivity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components.
• Ligand Synthesis: Intermediate for creating specialized organometallic catalysts and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: Fundamental reagent for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-1-[(4-Methylphenyl)Sulfonyl]-2-(Tributylstannyl)-
CAS No.	882033-58-1
Molecular Formula	C26H37FN2O2SSn
Molecular Weight	587.33 g/mol
Synonyms	5-Fluoro-1-(p-tolylsulfonyl)-2-(tributylstannyl)-1H-pyrrolo[2,3-b]pyridine; 2-Tributylstannyl-5-fluoro-1-tosyl-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-1-tosyl-2-(tributylstannyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-1-[(4-methylphenyl)sulfonyl]-2-(tributylstannyl)-; Tributyl[5-fluoro-1-(4-methylphenyl)sulfonyl-1H-pyrrolo[2,3-b]pyridin-2-yl]stannane; Stannane, tributyl[5-fluoro-1-[(4-methylphenyl)sulfonyl]-1H-pyrrolo[2,3-b]pyridin-2-yl]-
EINECS	Contact for details

Quality Control

Every batch of our 1H-Pyrrolo[2,3-B]Pyridine, 5-Fluoro-1-[(4-Methylphenyl)Sulfonyl]-2-(Tributylstannyl)- is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. A detailed Certificate of Analysis (COA) including assay (by HPLC/NMR), identity confirmation, and impurity profile is supplied with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to prevent oxidation and degradation. The material is light-sensitive and easily oxidized. Keep the container tightly sealed in a cool, dry, and well-ventilated place. Separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Tin (Sn) Content	20.0 - 21.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.