Description

4-(2-Thienyl)Tetrahydro-2H-Pyran-4-Carbonitrile is a high-value heterocyclic building block containing both thiophene and tetrahydropyran moieties. This compound is essential for advanced pharmaceutical research and fine chemical synthesis, serving as a critical intermediate in the development of novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its unique heterocyclic structure for bioactivity.
• Material Science Precursor: Serves as a monomer or functional additive in the synthesis of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Utilized in organometallic chemistry to create novel ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	4-(2-Thienyl)Tetrahydro-2H-Pyran-4-Carbonitrile
CAS No.	880166-17-6
Molecular Formula	C10H11NOS
Molecular Weight	193.26 g/mol
Synonyms	4-(Thiophen-2-yl)tetrahydro-2H-pyran-4-carbonitrile; 4-(2-Thienyl)-4-cyanotetrahydropyran; 4-Cyano-4-(2-thienyl)tetrahydropyran; Tetrahydro-4-(2-thienyl)-2H-pyran-4-carbonitrile; 4-(2-Thienyl)tetrahydropyran-4-carbonitrile; 880166-17-6; 4-(Thiophen-2-yl)oxane-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(2-Thienyl)Tetrahydro-2H-Pyran-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can adhere to cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.