Description

Methyl 5-Fluoro-3-Methylbenzofuran-2-Carboxylate is a high-purity fluorinated benzofuran derivative, a crucial building block in advanced organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate the benzofuran scaffold with fluorine and ester functionalities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the benzofuran core and fluorine atom can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for the synthesis of functional organic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	Methyl 5-Fluoro-3-Methylbenzofuran-2-Carboxylate
CAS No.	879925-30-1
Molecular Formula	C12H11FO3
Molecular Weight	222.21 g/mol
Synonyms	5-Fluoro-3-methyl-1-benzofuran-2-carboxylic acid methyl ester; Methyl 5-fluoro-3-methyl-1-benzofuran-2-carboxylate; 2-Benzofurancarboxylic acid, 5-fluoro-3-methyl-, methyl ester; 879925-30-1; 5-Fluoro-3-methylbenzofuran-2-carboxylic acid methyl ester; 3-Methyl-5-fluorobenzofuran-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Fluoro-3-Methylbenzofuran-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high standards, including cGMP for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.