Description

5-Piperazin-1-Ylmethyl-Furan-2-Carboxylic Acid is a high-value heterocyclic building block and pharmaceutical intermediate of significant interest in modern organic synthesis. Its unique molecular architecture, featuring both a piperazine and a furan carboxylic acid moiety, makes it a versatile synthon for constructing complex molecules with potential biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Chemical Research & Development: Used as a key starting material or advanced intermediate in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis or metal-organic frameworks (MOFs) due to its chelating potential from the piperazine nitrogen atoms.
• Fine Chemical Production: Integral to the multi-step synthesis of specialized fine chemicals and agrochemical intermediates requiring a fused heterocyclic structure.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling to amines, making it useful for creating biochemical probes, labeled compounds, or peptide mimetics.

Basic Information

Product Name	5-Piperazin-1-Ylmethyl-Furan-2-Carboxylic Acid
CAS No.	878431-40-4
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	5-[(Piperazin-1-yl)methyl]furan-2-carboxylic acid; 5-(Piperazin-1-ylmethyl)furan-2-carboxylic acid; 5-(Piperazin-1-ylmethyl)-2-furancarboxylic acid; Furan-2-carboxylic acid, 5-(piperazin-1-ylmethyl)-; 878431-40-4; 5-Piperazin-1-ylmethyl-2-furoic acid
EINECS	Contact for details

Quality Control

Every batch of 5-Piperazin-1-Ylmethyl-Furan-2-Carboxylic Acid is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure the material meets the precise requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed when not in use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.