Description

1-[(6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Yl)Carbonyl]Piperidine is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development programs targeting novel therapeutic agents, particularly in the central nervous system (CNS) and cardiovascular domains. It is an essential building block for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking reliable, high-quality raw materials.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for neurological and cardiovascular applications.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes in drug discovery.
• Process Chemistry & Scale-Up: Serves as a critical raw material for process research, development, and the commercial-scale manufacturing of APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical market.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in API production.

Basic Information

Product Name	1-[(6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Yl)Carbonyl]Piperidine
CAS No.	878208-57-2
Molecular Formula	C15H18FNO2
Molecular Weight	263.31 g/mol
Synonyms	6-Fluoro-2-(piperidine-1-carbonyl)chroman; 1-(6-Fluoro-2H-chromene-2-carbonyl)piperidine; 1-(6-Fluoro-3,4-dihydro-2H-chromene-2-carbonyl)piperidine; 1-(6-Fluoro-2-oxo-2H-chromen-3-yl)piperidine (tautomer); FPP (abbreviation); 878208-57-2; Piperidine, 1-[(6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)carbonyl]-
EINECS	Contact for details

Quality Control

Our 1-[(6-Fluoro-3,4-Dihydro-2H-1-Benzopyran-2-Yl)Carbonyl]Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring a reliable supply for demanding pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.