Description

2,6-Difluorobenzyl Mercaptan is a versatile organosulfur and organofluorine building block, essential for advanced chemical synthesis. Its value lies in the unique reactivity of the thiol (-SH) group combined with the electronic influence of the difluoro substitution on the aromatic ring, enabling precise molecular construction. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Ligand and Catalyst Precursor: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Polymer Modification: Employed to introduce thiol functional groups into polymer backbones or as a chain-transfer agent in controlled radical polymerizations.
• Material Science Research: Utilized in the creation of self-assembled monolayers (SAMs) and surface modification agents for sensors and electronic components.
• Custom Chemical Synthesis: A valuable building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	2,6-Difluorobenzyl Mercaptan
CAS No.	878204-82-1
Molecular Formula	C7H6F2S
Molecular Weight	160.19 g/mol
Synonyms	(2,6-Difluorophenyl)methanethiol; 2,6-Difluorobenzylthiol; 1-(2,6-Difluorophenyl)methanethiol; α-Mercapto-2,6-difluorotoluene; 2,6-Difluoro-α-toluenethiol; 2,6-Difluorobenzyl Mercaptan; 2,6-Difluorobenzylmercaptan; 2,6-Difluorophenylmethanethiol
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluorobenzyl Mercaptan is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets your specific research or production requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.