Description

F-Amidine (Trifluoroacetate Salt) is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. This compound is valued for its role as a key building block in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting metabolic and central nervous system disorders.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators requiring specific fluorine-containing motifs.
• Peptide Mimetics & Drug Discovery: Serves as a precursor for creating peptide analogs and other bioactive compounds where the amidine functionality is essential for target binding.
• Material Science: Employed in the synthesis of specialty polymers and advanced materials that benefit from fluorine incorporation for enhanced stability or performance.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up campaigns in fine chemical production.

Basic Information

Product Name	F-Amidine (Trifluoroacetate Salt)
CAS No.	877617-46-4
Molecular Formula	C3H4F3N3O2
Molecular Weight	171.08 g/mol
Synonyms	Formamidine, 2-fluoro-, trifluoroacetate (salt); 2-Fluoroformamidine trifluoroacetate; 2-Fluoroformimidamide trifluoroacetate; F-Amidine TFA Salt; (2-Fluoroformimidamidonium) trifluoroacetate
EINECS	Contact for details

Quality Control

Our F-Amidine (Trifluoroacetate Salt) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach ambient temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.