Description

F-Amidine is a specialized fluorinated organic compound, identified by CAS NO 877617-45-3, that serves as a high-value building block in advanced chemical synthesis. Its unique molecular structure, featuring both fluorine and amidine functional groups, makes it a critical intermediate for creating compounds with enhanced biological activity and material properties. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce fluorine motifs for improved metabolic stability, lipophilicity, or electronic characteristics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the fluorine atom enhances bioavailability and environmental persistence.
• Material Science Research: Serves as a precursor for fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric properties or chemical resistance.
• Chemical Biology & Proteomics: Employed as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the amidine functionality into complex molecules under mild conditions.
• Fluorine Chemistry Research: A valuable compound for academic and industrial research focused on the synthesis and application of organofluorine compounds.

Basic Information

Product Name	F-Amidine
CAS No.	877617-45-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Fluoroamidine; 877617-45-3; F-Amidine reagent; Fluorinated amidine; Amidino fluoride derivative; (Fluorophenyl)amidine; Research chemical 877617-45-3
EINECS	Contact for details

Quality Control

Every batch of F-Amidine CAS NO 877617-45-3 is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.