Description

(αr, α'R,2R,2'S)-Rel-α, α '-[[(Phenylmethyl)Imino] Bis(Methylene)]Bis[6-Fluoro-3,4-Dihydro-2H- 1-Benzopyran-2-Methanol] is a sophisticated chiral organic compound featuring a bis(benzopyran) structure linked by an imino bis(methylene) bridge, with the CAS registry number 876666-07-8. This compound matters as a high-value pharmaceutical intermediate or research chemical, prized for its defined stereochemistry and complex molecular architecture which are critical for biological activity studies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of novel therapeutic agents, particularly in areas requiring enantiomerically pure scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), especially for central nervous system or cardiovascular targets.
• Chiral Ligand or Catalyst Precursor: Potential use in asymmetric synthesis due to its multiple stereocenters and nitrogen/oxygen donor atoms.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Biochemical Probe: Utilized in biochemical assays to investigate enzyme inhibition or receptor binding mechanisms.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, fluorinated organic molecules with specific optical properties.

Basic Information

Item	Details
Product Name	(αr, α'R,2R,2'S)-Rel-α, α '-[[(Phenylmethyl)Imino] Bis(Methylene)]Bis[6-Fluoro-3,4-Dihydro-2H- 1-Benzopyran-2-Methanol]
CAS No.	876666-07-8
Molecular Formula	C37H37F2NO6
Molecular Weight	629.70 g/mol
Synonyms	Rel-(Ar,α'R,2R,2'S)-α,α'-[[(Phenylmethyl)imino]bis(methylene)]bis[6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol]; 876666-07-8; Bis(6-fluoro-2-hydroxymethylchroman) benzylimino dimethyl ether (stereospecific); (R,R)-Bis(6-fluoro-2-hydroxymethylchroman-2-yl)methyl benzylamine; Benzylimino-bis(methylene)-bis(6-fluoro-3,4-dihydro-2H-chromene-2-methanol) (specific isomer); A chiral bis(benzopyran) derivative.
EINECS	Contact for details

Quality Control

Our (αr, α'R,2R,2'S)-Rel-α, α '-[[(Phenylmethyl)Imino] Bis(Methylene)]Bis[6-Fluoro-3,4-Dihydro-2H- 1-Benzopyran-2-Methanol] is produced under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from chiral HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.