Description

(R)-1-(3-Fluorobenzyl)Pyrrolidin-3-Amine, Dihydrochloride is a high-purity chiral amine building block and pharmaceutical intermediate. Its value lies in its specific stereochemistry and functional groups, which are critical for the synthesis of targeted bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those working on central nervous system (CNS) agents, receptor modulators, and other fine chemical syntheses.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a building block for designing and synthesizing receptor ligands and enzyme inhibitors in medicinal chemistry.
• Asymmetric Synthesis: Serves as a chiral precursor or catalyst in stereoselective chemical reactions.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Utilized in the synthesis of candidate compounds for pharmacological screening and early-stage drug development.

Basic Information

Product Name	(R)-1-(3-Fluorobenzyl)Pyrrolidin-3-Amine, Dihydrochloride
CAS No.	876162-17-3
Molecular Formula	C11H16Cl2FN2
Molecular Weight	263.16 g/mol
Synonyms	(3R)-1-[(3-Fluorophenyl)methyl]-3-pyrrolidinamine dihydrochloride; (R)-1-(3-Fluorobenzyl)-3-aminopyrrolidine dihydrochloride; (R)-3-Amino-1-(3-fluorobenzyl)pyrrolidine dihydrochloride; 1-[(3-Fluorophenyl)methyl]-3-pyrrolidinamine, (3R)-, hydrochloride (1:2); UNII-7Y4K1J1Q3P; 876162-17-3; (R)-1-(3-Fluorobenzyl)pyrrolidin-3-amine 2HCl
EINECS	Contact for details

Quality Control

Our (R)-1-(3-Fluorobenzyl)Pyrrolidin-3-Amine, Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.