Description

4-Chloro-6-(Tributylstannyl)-Thieno[3,2-D]Pyrimidine is a high-value organotin intermediate featuring a fused thienopyrimidine heterocyclic core. This compound matters for its role as a versatile building block in advanced organic synthesis, particularly in cross-coupling reactions like the Stille coupling. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinases and other enzymes.
• Agrochemical Research: Used to create new classes of herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a monomer or building block for developing organic electronic materials, such as semiconductors for OLEDs or OFETs.
• Stille Coupling Reactions: The tributylstannyl group makes it an excellent partner for palladium-catalyzed cross-coupling with aryl or vinyl halides, enabling efficient carbon-carbon bond formation.
• Chemical Biology Probes: Utilized in the development of labeled compounds or molecular probes for studying biological pathways.
• Ligand Synthesis: Can be functionalized to create novel ligands for catalysis or metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	4-Chloro-6-(Tributylstannyl)-Thieno[3,2-D]Pyrimidine
CAS No.	875339-90-5
Molecular Formula	C18H29ClN2SSn
Molecular Weight	483.82 g/mol
Synonyms	4-Chloro-6-(tributylstannyl)thieno[3,2-d]pyrimidine; 4-Chloro-6-tributylstannanylthieno[3,2-d]pyrimidine; Thieno[3,2-d]pyrimidine, 4-chloro-6-(tributylstannyl)-; 6-Tributylstannyl-4-chlorothieno[3,2-d]pyrimidine; 4-Chloro-6-tributylstannyl-thieno[3,2-d]pyrimidine; 875339-90-5; 4-Chloro-6-(tributylstannyl)thieno[3,2-d]pyrimidine (Stille reagent)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and stability. Certificates of Analysis (COA) detailing specifications and test results are available upon request. We adhere to a cGMP-compliant quality management system for products intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, as organotin compounds can be sensitive to oxygen and moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.