Description

7-Chloro-2-Tributylstannanyl-Thieno[3,2-B]Pyridine is a high-value organotin intermediate, specifically a stannylated heterocyclic compound, that serves as a critical building block in advanced organic synthesis. Its core value lies in enabling efficient cross-coupling reactions, such as the Stille reaction, which are fundamental for constructing complex molecular architectures in research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require precise and reliable organometallic reagents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates containing the thienopyridine scaffold.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides through structure-activity relationship (SAR) studies.
• Material Science: Building block for creating organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs).
• Stille Cross-Coupling Reactions: Acts as a versatile organotin donor for the palladium-catalyzed formation of carbon-carbon bonds under mild conditions.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds for target identification and mechanistic studies.
• Catalyst Ligand Development: Serves as a precursor for novel ligand systems in transition metal catalysis.

Basic Information

Product Name	7-Chloro-2-Tributylstannanyl-Thieno[3,2-B]Pyridine
CAS No.	875339-66-5
Molecular Formula	C19H30ClNSn
Molecular Weight	430.60 g/mol
Synonyms	2-Tributylstannanyl-7-chlorothieno[3,2-b]pyridine; 7-Chloro-2-(tributylstannyl)thieno[3,2-b]pyridine; Tributyl(7-chlorothieno[3,2-b]pyridin-2-yl)stannane; 7-Chloro-2-tributylstannylthieno[3,2-b]pyridine; Stannane, tributyl(7-chlorothieno[3,2-b]pyridin-2-yl)-; 875339-66-5; (7-Chlorothieno[3,2-b]pyridin-2-yl)tributylstannane
EINECS	Contact for details

Quality Control

Our 7-Chloro-2-Tributylstannanyl-Thieno[3,2-B]Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including NMR (1H, 13C, 119Sn) and HPLC analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is between 2°C and 8°C. Keep away from strong bases and incompatible materials. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Tin (Sn) Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.