Description

4-(Difluoromethoxy)Benzenesulfonamide is a specialized organofluorine compound featuring a difluoromethoxy-substituted benzenesulfonamide core structure. This unique molecular architecture makes it a valuable intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), particularly in areas requiring enhanced metabolic stability and lipophilicity. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the development of new drug candidates, especially sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides with improved efficacy.
• Material Science Research: Serves as a precursor for functional polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probes: Employed in the design of enzyme inhibitors and molecular probes for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical synthesis projects.

Basic Information

Product Name	4-(Difluoromethoxy)Benzenesulfonamide
CAS No.	874781-09-6
Molecular Formula	C7H7F2NO3S
Molecular Weight	223.20 g/mol
Synonyms	p-(Difluoromethoxy)benzenesulfonamide; Benzenesulfonamide, 4-(difluoromethoxy)-; 4-(Difluoromethoxy)benzene-1-sulfonamide; 1-(Difluoromethoxy)-4-sulfamoylbenzene
EINECS	Contact for details

Quality Control

Our 4-(Difluoromethoxy)Benzenesulfonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.