Description

Ethyl 6-Chloro-2-Phenylimidazo[1,2-B]Pyridazine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 874779-81-4. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its imidazopyridazine core which is a privileged scaffold in drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly for applications in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Drug Discovery & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Oncology Research: Used in the development of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Development: Employed in research programs focused on neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	Ethyl 6-Chloro-2-Phenylimidazo[1,2-B]Pyridazine-3-Carboxylate
CAS No.	874779-81-4
Molecular Formula	C15H12ClN3O2
Molecular Weight	301.73 g/mol
Synonyms	6-Chloro-2-phenylimidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester; Ethyl 6-chloro-2-phenylimidazo[1,2-b]pyridazine-3-carboxylate; Imidazo[1,2-b]pyridazine-3-carboxylic acid, 6-chloro-2-phenyl-, ethyl ester; 874779-81-4; 6-Chloro-2-phenyl-imidazo[1,2-b]pyridazine-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Chloro-2-Phenylimidazo[1,2-B]Pyridazine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with the standards required for pharmaceutical R&D and cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.