Description

2-(But-3-Ynyl)Malonic Acid is a specialized malonic acid derivative featuring a terminal alkyne functional group, making it a valuable bifunctional building block in organic synthesis. This compound is significant for its role in facilitating carbon-carbon bond formation and serving as a precursor for complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications such as drug discovery and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of active pharmaceutical ingredients (APIs) and complex heterocycles via cyclization and coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Biology & Proteomics: The terminal alkyne group enables its use in click chemistry (e.g., CuAAC) for bioconjugation and labeling applications.
• Organic Synthesis Building Block: Employed in Knoevenagel condensations and decarboxylative coupling reactions to introduce functionalized alkyl chains.
• Academic & Industrial R&D: A versatile reagent for methodological development and exploring new synthetic pathways in laboratory settings.

Basic Information

Product Name	2-(But-3-Ynyl)Malonic Acid
CAS No.	872791-03-2
Molecular Formula	C7H8O4
Molecular Weight	156.14 g/mol
Synonyms	2-(But-3-yn-1-yl)malonic acid; 2-(3-Butynyl)malonic acid; Propargylmalonic acid derivative; 3-Butynylmalonic acid; Malonic acid, 2-(3-butynyl)-; 872791-03-2; (But-3-ynyl)propanedioic acid
EINECS	Contact for details

Quality Control

Our 2-(But-3-Ynyl)Malonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.