Description

5-Trifluoromethyl-Pyridazine-4-Carboxylic Acid Methyl Ester is a high-value fluorinated pyridazine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, making it indispensable for modern pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a starting material for creating fluorinated heterocyclic compounds used in organic electronics and functional materials.
• Chemical Biology Probe Development: Utilized in medicinal chemistry for creating labeled compounds and probes to study biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital intermediate for fine chemical suppliers offering bespoke synthesis services to global clients.

Basic Information

Product Name	5-Trifluoromethyl-Pyridazine-4-Carboxylic Acid Methyl Ester
CAS No.	872780-97-7
Molecular Formula	C8H5F3N2O2
Molecular Weight	218.13 g/mol
Synonyms	Methyl 5-(trifluoromethyl)pyridazine-4-carboxylate; 5-(Trifluoromethyl)-4-pyridazinecarboxylic acid methyl ester; 4-Pyridazinecarboxylic acid, 5-(trifluoromethyl)-, methyl ester; Methyl 5-trifluoromethyl-4-pyridazinecarboxylate; 5-Trifluoromethyl-4-pyridazinecarboxylic acid methyl ester; 872780-97-7; 5-Trifluoromethylpyridazine-4-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our 5-Trifluoromethyl-Pyridazine-4-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We support development and commercial projects with material that meets stringent internal specifications, suitable for use in GMP starting material applications upon qualification.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.