Description

1-[(S)-2-Hydroxy-1-Phenylethyl]-3-(2,4,6-Trimethylphenyl)-4,5-Dihydro-1H-Imidazolium Hexafluorophosphate is a high-purity, chiral imidazolium salt primarily utilized as a sophisticated organocatalyst or chiral ligand in asymmetric synthesis. Its value lies in enabling the production of enantiomerically pure intermediates, which are critical for the development of pharmaceuticals and advanced materials. This compound is essential for research institutions and industrial chemists working in pharmaceutical development, fine chemical synthesis, and academic research where precise stereochemical control is paramount.

Application

• Asymmetric Organocatalysis: Employed as a key catalyst for enantioselective C-C and C-X bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Facilitates the production of chiral active pharmaceutical ingredients (APIs) and key synthons.
• Chiral Ligand in Metal Complexes: Used to modify metal catalysts for enhanced stereoselectivity in hydrogenation and cross-coupling reactions.
• Academic & Process Chemistry Research: A valuable tool for developing new synthetic methodologies and scaling up chiral processes.
• Fine Chemical Manufacturing: Applied in the synthesis of specialty chemicals requiring high enantiomeric purity.
• Material Science Research: Investigated for the development of chiral ionic liquids or functional materials.

Basic Information

Product Name	1-[(S)-2-Hydroxy-1-Phenylethyl]-3-(2,4,6-Trimethylphenyl)-4,5-Dihydro-1H-Imidazolium Hexafluorophosphate
CAS No.	872164-47-1
Molecular Formula	C20H25F6N2O2P
Molecular Weight	494.39 g/mol
Synonyms	(S)-1-(2-Hydroxy-1-phenylethyl)-3-(2,4,6-trimethylphenyl)-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate; (S)-1-Phenylethanol-derived Imidazolinium Hexafluorophosphate; Chiral Imidazolinium Salt; Asymmetric Organocatalyst Precursor; (S)-TMS-Imidazolinium Hexafluorophosphate; (S)-1-(1-Hydroxy-1-phenylpropan-2-yl)-3-mesitylimidazolinium Hexafluorophosphate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (ee), and impurity profiles are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.