Description

Methyl 2-((2R,4As,6S,7S,8R,8Ar)-7,8- Dihydroxy-6-((S,E)-1-Hydroxy-3- (Trimethylsilyl)Allyl)Octahydropyrano[3,2 -B]Pyran-2-Yl)Acetate is a sophisticated, high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. This compound matters for its precise stereochemistry and functional groups, which enable the construction of complex molecular architectures with high selectivity. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and natural product analogs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in antiviral, anticancer, and anti-infective drug discovery programs.
• Agrochemical Synthesis: Used in the construction of complex, bioactive molecules for advanced crop protection agents and pesticides.
• Natural Product Synthesis: Serves as a critical building block in the total synthesis of complex natural products and their derivatives for biological evaluation.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the efficient, scalable production of target molecules under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology & Probe Development: Utilized to create molecular probes and labeled compounds for studying biological pathways and mechanisms of action.
• Academic & Contract Research: A valuable reagent for universities and Contract Research Organizations (CROs) conducting cutting-edge synthetic methodology and medicinal chemistry research.

Basic Information

Product Name	Methyl 2-((2R,4As,6S,7S,8R,8Ar)-7,8- Dihydroxy-6-((S,E)-1-Hydroxy-3- (Trimethylsilyl)Allyl)Octahydropyrano[3,2 -B]Pyran-2-Yl)Acetate
CAS No.	871360-33-7
Molecular Formula	C19H34O7Si
Molecular Weight	402.56 g/mol
Synonyms	Methyl (2R,4aR,6S,7S,8R,8aR)-7,8-dihydroxy-6-[(1S,2E)-1-hydroxy-3-(trimethylsilyl)prop-2-en-1-yl]tetrahydro-2H,4aH-pyrano[3,2-b]pyran-2-acetate; (2R,4aR,6S,7S,8R,8aR)-Methyl 7,8-dihydroxy-6-[(1S,2E)-1-hydroxy-3-(trimethylsilyl)allyl]octahydropyrano[3,2-b]pyran-2-acetate; TMS-Allyl Pyran Acetate Derivative; Chiral Octahydropyran Building Block; CAS 871360-33-7
EINECS	Contact for details

Quality Control

Our Methyl 2-((2R,4As,6S,7S,8R,8Ar)-7,8- Dihydroxy-6-((S,E)-1-Hydroxy-3- (Trimethylsilyl)Allyl)Octahydropyrano[3,2 -B]Pyran-2-Yl)Acetate is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation from moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.