Description

1-Bromo-2-Chloro-3-(Methylsulfonyl)Benzene is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring bromo, chloro, and methylsulfonyl substituents, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the halogen and sulfone groups contribute to biological activity.
• Material Science Research: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive bromo and chloro substituents.
• Chemical Derivatization: The methylsulfonyl group can be further modified or reduced, enabling the synthesis of a diverse library of thioether and sulfide derivatives.

Basic Information

Product Name	1-Bromo-2-Chloro-3-(Methylsulfonyl)Benzene
CAS No.	871352-89-5
Molecular Formula	C7H6BrClO2S
Molecular Weight	269.54 g/mol
Synonyms	2-Bromo-1-Chloro-3-(Methylsulfonyl)Benzene; 3-Bromo-2-Chlorophenyl Methyl Sulfone; 1-Bromo-2-Chloro-3-Methanesulfonylbenzene; 2-Chloro-3-bromophenyl methyl sulphone; Methyl 3-Bromo-2-chlorophenyl sulfone; 871352-89-5; 3-(Methylsulfonyl)-1-bromo-2-chlorobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Chloro-3-(Methylsulfonyl)Benzene is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee supply consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.