Description

(3Ar,5R,6S,6Ar)-5-(2-Hydroxy-3-(Trimethylsilyl)Propyl)-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxol-6-Ol is a sophisticated chiral building block and protected sugar derivative of significant interest in advanced organic synthesis. Its core value lies in its unique stereochemistry and functional groups, which make it a critical intermediate for constructing complex, biologically active molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and other fine chemicals where precise stereocontrol is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel nucleoside-based therapeutics, including potential antiviral and anticancer agents.
• Advanced Organic Synthesis: Serves as a protected sugar moiety for the stereoselective construction of complex natural products and glycoconjugates.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Biochemical Research: Employed in studies exploring carbohydrate-protein interactions and the synthesis of labeled probes for metabolic pathways.
• Fine Chemical Production: Acts as a precursor for specialized reagents and catalysts used in asymmetric synthesis.

Basic Information

Product Name	(3Ar,5R,6S,6Ar)-5-(2-Hydroxy-3-(Trimethylsilyl)Propyl)-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxol-6-Ol
CAS No.	871347-95-4
Molecular Formula	C15H30O5Si
Molecular Weight	318.49 g/mol
Synonyms	5-(2-Hydroxy-3-(Trimethylsilyl)propyl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol; (3aR,5R,6S,6aR)-5-[2-Hydroxy-3-(trimethylsilyl)propyl]-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-6-ol; Protected TMS-propyl glycoside derivative; Chiral isopropylidene acetal sugar intermediate; TMS-protected sugar alcohol; 871347-95-4; Tetrahydrofurodioxol derivative
EINECS	Contact for details

Quality Control

Our (3Ar,5R,6S,6Ar)-5-(2-Hydroxy-3-(Trimethylsilyl)Propyl)-2,2-Dimethyltetrahydrofuro[2,3-D][1,3]Dioxol-6-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.