Description

Tetrahydro-2H-Pyran-4-Carboxylic Acid Benzyl Ester is a versatile chiral building block and protected intermediate of significant value in advanced organic synthesis. Its structure, featuring a tetrahydro-2H-pyran ring and a benzyl-protected carboxylic acid group, makes it a critical precursor for constructing complex molecules with high stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in the development of central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Synthesis: Used as a building block in the production of advanced pesticides and herbicides requiring specific stereochemistry for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The protected acid moiety is valuable for constructing peptide analogs and peptidomimetic scaffolds in medicinal chemistry.
• Material Science Monomer: Can be utilized in the synthesis of specialized polymers and functional materials.
• Academic & Contract Research: A valuable reagent for methodological development and complex molecule construction in research laboratories.

Basic Information

Product Name	Tetrahydro-2H-Pyran-4-Carboxylic Acid Benzyl Ester
CAS No.	871022-58-1
Molecular Formula	C13H16O3
Molecular Weight	220.26 g/mol
Synonyms	Benzyl Tetrahydro-2H-Pyran-4-Carboxylate; 4-(Benzyloxycarbonyl)tetrahydro-2H-pyran; Tetrahydro-2H-pyran-4-carboxylic acid phenylmethyl ester; THP-OBn; Oxane-4-carboxylic acid benzyl ester; Benzyl Oxane-4-carboxylate; 871022-58-1
EINECS	Contact for details

Quality Control

Our Tetrahydro-2H-Pyran-4-Carboxylic Acid Benzyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.