Description

Potassium 2-Chlorophenyltrifluoroborate is an organotrifluoroborate salt, a highly valuable building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it a superior alternative to traditional boronic acids in cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it facilitates the efficient synthesis of complex, functionalized aromatic structures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this stable boronate ester precursor, crucial for constructing biaryl scaffolds in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the development and scale-up of active pharmaceutical ingredients (APIs), particularly those containing substituted biphenyl or heterobiaryl motifs.
• Agrochemical Product Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific chlorinated aromatic components.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Facilitates the creation of organic electronic materials, such as those used in OLEDs and conductive polymers, by enabling precise molecular architecture.
• Chemical Biology & Probe Development: Utilized in the labeling and modification of biomolecules or in the synthesis of molecular probes for diagnostic applications.

Basic Information

Product Name	Potassium 2-Chlorophenyltrifluoroborate
CAS No.	870195-98-5
Molecular Formula	C6H4BClF3K
Molecular Weight	218.45 g/mol
Synonyms	Potassium (2-Chlorophenyl)trifluoroborate; 2-Chlorophenyltrifluoroborate Potassium Salt; Potassium 2-Chlorobenzene-1-trifluoroborate; (2-Chlorophenyl)trifluoroboronic Acid Potassium Salt; 2-Chloro-Benzenetrifluoroborate Potassium; 2-Chloro-Benzeneboronic Acid Trifluoroborate Potassium Complex; 2-Chloro-Benzeneboronic Acid Potassium Trifluoroborate Salt; 2-Chlorophenyl-BF3K
EINECS	Contact for details

Quality Control

Our Potassium 2-Chlorophenyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F), HPLC for purity assessment, and KF titration for moisture content, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) with full analytical data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) in a controlled environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
¹¹B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility Test	Soluble in common polar aprotic solvents (e.g., DMF, DMSO)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.