Description

n-Dodecylzinc Bromide is a highly reactive organozinc reagent, specifically an alkylzinc halide, widely utilized in organic synthesis. Its primary value lies in its ability to act as a nucleophilic dodecyl anion equivalent, enabling efficient carbon-carbon bond formation under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for the synthesis of complex molecules and fine chemicals.

Application

• Negishi Cross-Coupling Reactions: A key reagent for coupling with aryl, vinyl, or alkynyl halides to construct C(sp2)-C(sp3) and C(sp3)-C(sp3) bonds.
• Pharmaceutical Intermediate Synthesis: Used in the preparation of active pharmaceutical ingredients (APIs) requiring long alkyl chain incorporation.
• Agrochemical Manufacturing: Employed in the synthesis of herbicides, fungicides, and plant growth regulators with specific lipid-soluble properties.
• Material Science & Polymer Chemistry: Serves as an initiator or chain-transfer agent in the synthesis of specialized polymers and functionalized nanomaterials.
• Organic Ligand Preparation: Useful for the alkylation of heteroatoms or metal centers to create novel ligands for catalysis.
• Fine Chemical Production: Applied in the manufacture of flavors, fragrances, and liquid crystals where precise alkylation is critical.

Basic Information

Product Name	n-Dodecylzinc Bromide
CAS No.	869589-06-0
Molecular Formula	C₁₂H₂₅BrZn
Molecular Weight	314.62 g/mol
Synonyms	Dodecylzinc Bromide; Zinc, bromododecyl-; Bromododecylzinc; Laurylzinc Bromide; 1-Bromozincdodecane; n-C12H25ZnBr; Alkylzinc Bromide C12
EINECS	Contact for details

Quality Control

Our n-Dodecylzinc Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and solution concentration. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by titration), zinc content, and bromide content is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. Due to its sensitivity to moisture and oxygen, the reagent should be handled in a dry, inert environment. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (GC)	≥ 95% (by GC, on solvent-free basis)
Zinc Content	Conforms to theoretical
Bromide Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.