Description

5-(Tributylstannyl)-2-(Triisopropylsilyl)Oxazole is a highly functionalized organotin and organosilicon reagent, specifically designed for advanced synthetic chemistry. This compound is critical for facilitating challenging cross-coupling reactions and constructing complex heterocyclic scaffolds. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex drug candidates, particularly those containing oxazole or other nitrogen-containing heterocycles.
• Stille Cross-Coupling Reactions: Serves as a versatile organotin reagent for palladium-catalyzed coupling with aryl, heteroaryl, and vinyl halides/triflates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring precise molecular architecture.
• Material Science Research: Employed in the creation of organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological pathways and protein interactions.
• Process Chemistry Development: Enables scalable routes to target molecules in pilot plant and manufacturing settings.

Basic Information

Item	Details
Product Name	5-(Tributylstannyl)-2-(Triisopropylsilyl)Oxazole
CAS No.	869542-43-8
Molecular Formula	C24H49NOSiSn
Molecular Weight	514.43 g/mol
Synonyms	2-(Triisopropylsilyl)-5-(tributylstannyl)oxazole; 5-Tributylstannyl-2-triisopropylsilyloxazole; Oxazole, 5-(tributylstannyl)-2-(triisopropylsilyl)-; TIPS-5-Stannyloxazole; (5-(Tributylstannyl)oxazol-2-yl)triisopropylsilane
EINECS	Contact for details

Quality Control

Every batch of 5-(Tributylstannyl)-2-(Triisopropylsilyl)Oxazole is produced and analyzed under strict quality management protocols to ensure consistency and reliability for sensitive synthetic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.