Description

[2-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridin-4-Yl]Methylamine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridine-pyran hybrid structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, agrochemicals, and specialty fine chemicals. Our supply is backed by stringent quality control to ensure batch-to-batch consistency for your most demanding synthesis protocols.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	[2-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridin-4-Yl]Methylamine
CAS No.	869293-80-1
Molecular Formula	C11H16N2O2
Molecular Weight	208.26 g/mol
Synonyms	4-(Aminomethyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]pyridine; 2-[(Oxan-4-yl)oxy]-4-pyridinemethanamine; (2-((Tetrahydro-2H-pyran-4-yl)oxy)pyridin-4-yl)methanamine; 4-Pyridinemethanamine, 2-[(tetrahydro-2H-pyran-4-yl)oxy]-; THP-Protected Aminopyridine Derivative; CAS 869293-80-1
EINECS	Contact for details

Quality Control

Every batch of [2-(Tetrahydro-2H-Pyran-4-Yloxy)Pyridin-4-Yl]Methylamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to support its use in cGMP and non-GMP applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as purity (by HPLC), identity (by IR, NMR), and impurity profiles. Our quality commitment ensures the material meets the high standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.