Description

2-Amino-2-(Tetrahydro-2H-Pyran-4-Yl)Acetic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. Its unique structure, featuring a tetrahydro-2H-pyran ring, makes it a valuable chiral building block for the development of novel pharmaceutical compounds and bioactive molecules. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create complex, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetics & Drug Design: Used to incorporate constrained, ring-based amino acid analogs into peptide backbones to enhance metabolic stability, bioavailability, and receptor selectivity.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators with specific chiral activity.
• Ligand & Catalyst Development: Employed in the creation of novel chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high-purity, complex amino acid derivatives.

Basic Information

Product Name	2-Amino-2-(Tetrahydro-2H-Pyran-4-Yl)Acetic Acid Hydrochloride
CAS No.	868748-75-8
Molecular Formula	C7H14ClNO3
Molecular Weight	195.64 g/mol
Synonyms	2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid hydrochloride; 4-Piperidineacetic acid, α-amino-, hydrochloride, tetrahydro-2H-pyran-4-yl derivative; (2-Amino-2-(tetrahydro-2H-pyran-4-yl)acetic acid) hydrochloride; 2-Amino-2-(oxan-4-yl)acetic acid hydrochloride; 868748-75-8; ATHEAA HCl; 2-(Tetrahydro-2H-pyran-4-yl)glycine hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(Tetrahydro-2H-Pyran-4-Yl)Acetic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.