Description

[12]Anens3, n-[3-(1,4,7-Trithia-10-Aza-10-Cyclododecyl)Propyl]Dansylamide is a sophisticated, high-purity chemical compound designed for advanced research and development applications. This dansylamide-functionalized macrocyclic derivative is valued for its unique photophysical properties and its role as a selective binding agent for metal ions and biological targets. It is primarily utilized by researchers and scientists in the fields of analytical chemistry, sensor development, and pharmaceutical discovery. The compound's structure makes it an excellent candidate for fluorescence-based assays, molecular recognition studies, and as a precursor for specialized diagnostic reagents.

Application

• Fluorescent Chemosensors: Acts as a signaling unit in the development of selective fluorescent probes for the detection of transition and heavy metal ions (e.g., Hg²⁺, Pb²⁺, Cd²⁺).
• Bioconjugation & Labeling: Used to label biomolecules (proteins, peptides) via its dansylamide moiety for fluorescence microscopy, immunoassays, and cellular imaging studies.
• Supramolecular Chemistry: Serves as a building block for constructing complex host-guest systems due to its thia-aza macrocyclic core, which can encapsulate specific cations or small molecules.
• Pharmaceutical Research: Investigated as a potential precursor or intermediate in the synthesis of novel therapeutic agents targeting metal-related pathologies.
• Material Science: Incorporated into polymeric or silica-based matrices to create smart materials with sensing capabilities for environmental monitoring.
• Analytical Reagent: Employed as a derivatization agent in chromatography (HPLC, TLC) to enhance the detection of amines, amino acids, and other analytes.

Basic Information

Product Name	[12]Anens3, n-[3-(1,4,7-Trithia-10-Aza-10-Cyclododecyl)Propyl]Dansylamide
CAS No.	868365-96-2
Molecular Formula	C₂₈H₄₀N₄O₂S₄
Molecular Weight	600.89 g/mol
Synonyms	N-[3-(1,4,7-Trithia-10-aza-10-cyclododecyl)propyl]-5-(dimethylamino)naphthalene-1-sulfonamide; Dansylamide-[12]aneNS3 conjugate; 1,4,7-Trithia-10-azacyclododecane, 10-[3-[[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]amino]propyl]-; [12]aneNS3-Dansylamide; N-Dansyl-1-aza-4,7,10-trithiacyclododecane propylamine; Fluorescent [12]aneNS3 derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of [12]Anens3 is produced and analyzed under strict quality protocols to ensure consistency and high purity for research applications. Our standard grade typically meets a purity specification of ≥95% (by HPLC), with identity confirmed by spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results for purity, identity, and related substances are provided with each shipment. We support compliance with various research and development standards, and custom purity grades (e.g., ≥98%, ≥99%) can be manufactured upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. The compound is light-sensitive (store away from light) and should be handled under inert atmosphere when appropriate for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.