Description

2-(Tributylstannyl)Quinoline is a specialized organotin compound featuring a quinoline heterocycle, serving as a versatile reagent in advanced synthetic chemistry. Its core value lies in its ability to act as a nucleophilic stannyl transfer agent, facilitating efficient carbon-carbon and carbon-heteroatom bond formation. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for complex molecule synthesis, including the development of active pharmaceutical ingredients (APIs) and functional organic materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those containing the quinoline scaffold, which is prevalent in antimalarial and anticancer agents.
• Stille Coupling Reagent: Used as a pivotal reagent in palladium-catalyzed Stille cross-coupling reactions to construct biaryl and heteroaryl systems critical for advanced material and drug discovery.
• Agrochemical Synthesis: Employed in the research and production of novel pesticides and herbicides, where the quinoline moiety can impart specific biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a precursor for synthesizing electron-transport or emissive layer materials in OLED displays and lighting.
• Ligand Precursor: Can be utilized to develop novel organometallic catalysts and ligands for asymmetric synthesis and polymerization processes.
• Academic & Industrial R&D: A valuable tool for method development and exploratory synthesis in university laboratories and corporate R&D centers focused on organometallic chemistry.

Basic Information

Product Name	2-(Tributylstannyl)Quinoline
CAS No.	868286-21-9
Molecular Formula	C25H39NSn
Molecular Weight	488.29 g/mol
Synonyms	Quinoline, 2-(tributylstannyl)-; Tributyl(quinolin-2-yl)stannane; 2-Tributylstannylquinoline; 2-(Tri-n-butylstannyl)quinoline; Stannane, tributyl(2-quinolinyl)-; 2-Quinolyltributyltin; Tributyl(2-quinolyl)tin; 2-(Tributyltin)quinoline
EINECS	Contact for details

Quality Control

Our 2-(Tributylstannyl)Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹⁹Sn), HPLC, and GC analysis, to confirm identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to relevant industry standards and can support development under cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is between 2°C and 8°C. Keep away from strong bases and incompatible materials. Handle and store in accordance with all applicable local and international regulations for organotin compounds.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Tin (Sn) Content	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.