Description

(2,3-Difluoro-1,4-Phenylene)Bis(Trimethylsilane) is a high-purity organosilicon intermediate featuring a difluorophenylene core flanked by trimethylsilyl protecting groups. This compound is valued for its role as a critical building block in advanced organic synthesis, particularly in the development of pharmaceuticals, agrochemicals, and functional materials. It is essential for researchers and manufacturers in fine chemical, electronics, and life science industries requiring precise fluorinated aromatic precursors.

Application

• Pharmaceutical Intermediate: Key synthon for constructing complex fluorinated drug candidates, including kinase inhibitors and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the difluoro-phenylene moiety enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated aromatic units in electronic display materials, improving charge transport and thermal stability.
• Polymer & Specialty Chemicals: Building block for high-performance polymers, including polyimides and polyarylates, where fluorine incorporation improves chemical resistance and lowers dielectric constant.
• Cross-Coupling Reactions: Utilized in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to introduce the silyl-protected difluorophenylene unit into complex molecular architectures.
• Organic Semiconductor Research: Investigated as a component in the development of novel organic field-effect transistors (OFETs) and photovoltaic materials.

Basic Information

Product Name	(2,3-Difluoro-1,4-Phenylene)Bis(Trimethylsilane)
CAS No.	867366-94-7
Molecular Formula	C12H20F2Si2
Molecular Weight	258.46 g/mol
Synonyms	1,4-Bis(trimethylsilyl)-2,3-difluorobenzene; 2,3-Difluoro-1,4-bis(trimethylsilyl)benzene; 2,3-Difluoro-p-phenylenebis(trimethylsilane); 1,4-Bis(trimethylsilyl)-2,3-difluorobenzol; TMS-Difluorophenylene-TMS; DFPBS; Bis(trimethylsilyl)-2,3-difluorobenzene
EINECS	Contact for details

Quality Control

Our (2,3-Difluoro-1,4-Phenylene)Bis(Trimethylsilane) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.