Description

4-(tert-Butyldimethylsilyloxy)Cyclohex-1-Enyl Trifluoromethanesulfonate is a high-value, protected intermediate crucial for advanced organic synthesis. This compound matters because it provides a reactive triflate leaving group and a robust silyl-protected alcohol, enabling precise, multi-step transformations in complex molecule construction. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-purity building blocks for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly for introducing functionalized cyclohexene rings.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides requiring specific stereochemistry.
• Cross-Coupling Reactions: Serves as an excellent electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) due to its triflate group.
• Natural Product Synthesis: Employed in the stereoselective construction of intricate natural product scaffolds found in terpenes and alkaloids.
• Material Science Research: Acts as a precursor for creating functionalized monomers or ligands for advanced polymers and catalysts.
• Protecting Group Chemistry: The tert-butyldimethylsilyl (TBDMS) group allows for the selective protection and deprotection of alcohols during multi-step syntheses.

Basic Information

Product Name	4-(tert-Butyldimethylsilyloxy)Cyclohex-1-Enyl Trifluoromethanesulfonate
CAS No.	865869-24-5
Molecular Formula	C13H23F3O4SSi
Molecular Weight	360.46 g/mol
Synonyms	4-[(tert-Butyldimethylsilyl)oxy]-1-cyclohexen-1-yl trifluoromethanesulfonate; 4-(TBDMSO)-1-Cyclohexenyl Triflate; 4-(tert-Butyldimethylsiloxy)cyclohex-1-enyl triflate; Cyclohex-1-en-4-yloxy-tert-butyldimethylsilane trifluoromethanesulfonate; 4-(tert-Butyldimethylsilyloxy)-1-cyclohexenyl Trifluoromethanesulfonate; 4-(TBDMS-Oxy)cyclohexenyl Triflate; 865869-24-5
EINECS	Contact for details

Quality Control

Our 4-(tert-Butyldimethylsilyloxy)Cyclohex-1-Enyl Trifluoromethanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR (¹H, ¹³C), and GC-MS, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.