Description

(5-Chloropyridin-2-Yl)Methyl Methanesulfonate is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a key synthon in the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and fungicides, leveraging the pyridine moiety for biological activity.
• Chemical Research & Development: Serves as a versatile electrophile or functionalized pyridine precursor in organic synthesis, cross-coupling reactions, and material science.
• Ligand and Catalyst Preparation: Employed in the modification of pyridine-based ligands for metal catalysis and coordination chemistry applications.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions where required.

Basic Information

Product Name	(5-Chloropyridin-2-Yl)Methyl Methanesulfonate
CAS No.	864758-02-1
Molecular Formula	C8H8ClNO3S
Molecular Weight	233.67 g/mol
Synonyms	2-(Chloromethyl)-5-chloropyridine methanesulfonate; Methanesulfonic acid (5-chloro-2-pyridinyl)methyl ester; (5-Chloro-2-pyridinyl)methyl methanesulfonate; 5-Chloro-2-pyridinemethanol methanesulfonate ester; (5-Chloro-pyridin-2-yl)-methyl methanesulfonate; 864758-02-1; (5-Chloro-2-pyridyl)methyl mesylate
EINECS	Contact for details

Quality Control

Our (5-Chloropyridin-2-Yl)Methyl Methanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems support compliance with relevant standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.