Description

(1,3-Dioxolan-2-Ylethyl)Zinc Bromide is a highly reactive organozinc reagent, also known as a Reformatsky-type reagent, valued for its role in forming carbon-carbon bonds under mild conditions. Its core value proposition lies in enabling efficient and selective synthetic pathways, particularly for the construction of complex organic molecules and pharmaceutical intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the preparation of β-hydroxy esters and other complex chiral molecules via Reformatsky-type reactions.
• Agrochemical Active Ingredient Production: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific carbon chain extensions.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, flavors, and fragrances where controlled carbon-carbon bond formation is critical.
• Academic and Industrial R&D: Serves as a versatile tool in research laboratories for method development and exploring new synthetic routes.
• Material Science Precursor: Potential use in the synthesis of organic ligands and metal-organic frameworks (MOFs) for advanced material applications.

Basic Information

Product Name	(1,3-Dioxolan-2-Ylethyl)Zinc Bromide
CAS No.	864501-59-7
Molecular Formula	C5H9BrO2Zn
Molecular Weight	246.42 g/mol
Synonyms	2-(1,3-Dioxolan-2-yl)ethylzinc bromide; (2-(1,3-Dioxolan-2-yl)ethyl)zinc bromide; Zinc, bromo[2-(1,3-dioxolan-2-yl)ethyl]-; Reformatsky reagent, (1,3-dioxolan-2-ylethyl)zinc bromide; Acetal-protected bromoethylzinc reagent; 2-(2-Bromoethyl)-1,3-dioxolane zinc derivative
EINECS	Contact for details

Quality Control

Our (1,3-Dioxolan-2-Ylethyl)Zinc Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and solution concentration. Certificates of Analysis (COA) detailing specific results are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized (store under inert atmosphere) and highly volatile, this reagent is typically supplied and stored as a solution in a dry, aprotic solvent like tetrahydrofuran (THF) under an inert atmosphere (argon or nitrogen). Store the sealed container in a cool, dry, well-ventilated area, away from heat and ignition sources. For long-term stability, storage at 2-8°C is recommended. Keep away from moisture, strong acids, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in THF (or as specified)
Purity (Zn content)	≥ 95%
Water Content (KF)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.