Description

(S)-[(Diphenyl)-T-Butyldimethylsiloxymethyl]Pyrrolidine is a high-purity chiral pyrrolidine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a sterically hindered, enantiomerically pure scaffold for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the asymmetric synthesis of drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Catalyst Ligand Precursor: Used to develop novel chiral ligands for asymmetric catalysis, including hydrogenation and cross-coupling reactions.
• Advanced Material Research: Building block for creating chiral polymers or functionalized surfaces with specific optical or electronic properties.
• Agrochemical Synthesis: Intermediate in the production of enantiomerically pure pesticides and herbicides.
• Academic & R&D: Valuable reagent for methodological development in organic chemistry and stereoselective synthesis.

Basic Information

Product Name	(S)-[(Diphenyl)-T-Butyldimethylsiloxymethyl]Pyrrolidine
CAS No.	864466-71-7
Molecular Formula	C23H33NOSi
Molecular Weight	367.61 g/mol
Synonyms	(S)-2-[(Diphenyl)(tert-Butyldimethylsilyloxy)methyl]pyrrolidine; (S)-1-[(Diphenyl)(tert-Butyldimethylsiloxy)methyl]pyrrolidine; (S)-N-[(Diphenyl)(tert-Butyldimethylsilyloxy)methyl]pyrrolidine; (S)-α-[(tert-Butyldimethylsilyloxy)diphenylmethyl]pyrrolidine; TBDMS-protected diphenyl pyrrolidine alcohol; Chiral pyrrolidine silyl ether; 864466-71-7
EINECS	Contact for details

Quality Control

Our (S)-[(Diphenyl)-T-Butyldimethylsiloxymethyl]Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.