Description

2,3,4,5,6-Pentafluorophenyl Phenylmethanesulfonate is a specialized organofluorine building block and sulfonate ester reagent of significant interest in advanced synthetic chemistry. Its core value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This compound is essential for researchers and process chemists in fine chemical, pharmaceutical, and material science industries who require high-purity, reliable reagents for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl group enhances biological activity and stability.
• Material Science: Serves as a precursor for functional polymers and advanced materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in palladium-catalyzed reactions (e.g., Suzuki, Stille) for creating biaryl structures.
• Protecting Group Chemistry: Utilized in multi-step organic synthesis for the temporary protection of functional groups.
• Chemical Research & Development: A valuable reagent for method development and exploring new synthetic pathways in academic and industrial R&D laboratories.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl Phenylmethanesulfonate
CAS No.	864450-16-8
Molecular Formula	C₁₃H₇F₅O₃S
Molecular Weight	338.25 g/mol
Synonyms	Pentafluorophenyl Phenylmethanesulfonate; Benzylsulfonic Acid Pentafluorophenyl Ester; Phenylmethanesulfonic Acid 2,3,4,5,6-Pentafluorophenyl Ester; (Pentafluorophenyl)methyl Benzenesulfonate; 864450-16-8; PFPM; Pentafluorophenyl Benzylsulfonate
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl Phenylmethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; ensure containers are kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.