Description

1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-2-Oxo-n-[3-(Triethoxysilyl)Propyl]-, (3As,4S,6Ar)- is a specialized organosilane derivative that combines a biotin-like core with a reactive triethoxysilyl group. This unique molecular architecture makes it a critical coupling agent for creating stable, covalent linkages between organic molecules and inorganic surfaces. It is essential for researchers and manufacturers in advanced materials science who require precise surface functionalization. The compound is identified by CAS NO 863118-16-5.

Application

• Surface Modification Agent: For functionalizing silica, glass, metal oxides, and other inorganic surfaces to introduce biotin-binding sites.
• Biosensor Development: As a key linker molecule for immobilizing proteins, enzymes, or antibodies onto sensor chips and electrodes.
• Affinity Chromatography Media: For synthesizing stationary phases that selectively bind avidin, streptavidin, or NeutrAvidin for protein purification.
• Nanomaterial Functionalization: To coat nanoparticles (e.g., quantum dots, gold NPs, magnetic beads) for targeted drug delivery or diagnostic applications.
• Bio-conjugation and Labeling: Enables the stable attachment of biotinylated molecules to silanized surfaces in microarray and diagnostic assay platforms.
• Adhesion Promotion: Can be used in specialty coatings and composites to improve adhesion between organic polymers and inorganic substrates.
• Research & Development: A valuable building block in organic synthesis and materials chemistry for creating novel hybrid materials.

Basic Information

Product Name	1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-2-Oxo-n-[3-(Triethoxysilyl)Propyl]-, (3As,4S,6Ar)-
CAS No.	863118-16-5
Molecular Formula	C19H35N3O5SSi
Molecular Weight	445.64 g/mol
Synonyms	Biotin-PEG3-Silane; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(3-(triethoxysilyl)propyl)pentanamide; Biotinamidocaproylamido-3,6-dioxaoctyl-propyltriethoxysilane; Biotinylated Triethoxysilane; Biotin-PEG3-Triethoxysilane; N-[3-(Triethoxysilyl)propyl]biotinamide; Biotinamidohexanoyl-3,6-dioxaoctyltriethoxysilane
EINECS	Contact for details

Quality Control

Our production of 1H-Thieno[3,4-D]Imidazole-4-Pentanamide, Hexahydro-2-Oxo-n-[3-(Triethoxysilyl)Propyl]-, (3As,4S,6Ar)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and manufacturing applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and purity. We operate under a cGMP-compliant quality management system, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive). For long-term storage under inert atmosphere, please contact our technical team for specific recommendations. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.