Description

2-Bromo-5-Chloro-4-(Trifluoromethyl)Aniline is a high-value halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and halogen substitution pattern makes it an essential intermediate for developing active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced biological activity and physical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances lipophilicity and biological efficacy.
• Material Science: Serves as a precursor for functionalized monomers and ligands used in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and creating complex molecular architectures in medicinal and synthetic chemistry.

Basic Information

Product Name	2-Bromo-5-Chloro-4-(Trifluoromethyl)Aniline
CAS No.	863111-48-2
Molecular Formula	C7H4BrClF3N
Molecular Weight	274.47 g/mol
Synonyms	2-Bromo-5-chloro-4-(trifluoromethyl)benzenamine; 4-Amino-2-bromo-5-chlorobenzotrifluoride; 2-Bromo-5-chloro-α,α,α-trifluoro-p-toluidine; 2-Bromo-5-chloro-4-trifluoromethylaniline; Benzenamine, 2-bromo-5-chloro-4-(trifluoromethyl)-; 863111-48-2; 2-Br-5-Cl-4-CF3-aniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. This compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.