Description

1-(3,4-Dimethoxy-Phenyl)-Cyclopropanecarboxylic Acid is a high-purity, synthetically valuable organic building block. This compound is a key chiral intermediate in the synthesis of complex pharmaceutical molecules, offering a rigid cyclopropane ring system that can impart desirable metabolic stability and conformational constraints to drug candidates. It is primarily sought after by research and development teams, as well as process chemists, in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and production of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used as a building block in the development of advanced herbicides, fungicides, and insecticides, where the cyclopropane moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Material Science Research: Investigated as a monomer or additive for creating polymers with specific thermal or mechanical properties.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the synthesis of complex natural product analogs.

Basic Information

Product Name	1-(3,4-Dimethoxy-Phenyl)-Cyclopropanecarboxylic Acid
CAS No.	862821-16-7
Molecular Formula	C₁₂H₁₄O₄
Molecular Weight	222.24 g/mol
Synonyms	1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic acid; 1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylic Acid; 1-(3,4-Dimethoxyphenyl)cyclopropanecarboxylate; Cyclopropanecarboxylic acid, 1-(3,4-dimethoxyphenyl)-; 862821-16-7; (3,4-Dimethoxyphenyl)cyclopropanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(3,4-Dimethoxy-Phenyl)-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP (current Good Manufacturing Practice) requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.