Description

4-(Methylsulfonyl)Cyclohexanone is a high-value, functionalized cyclohexanone derivative characterized by its methylsulfonyl substituent, which imparts unique reactivity and polarity. This compound serves as a versatile and critical advanced pharmaceutical intermediate (API) and a key building block in sophisticated organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a building block for developing new generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis Building Block: The sulfone group acts as a versatile handle for further functionalization via nucleophilic substitution or as an activating group for adjacent carbon centers, enabling complex cyclization and coupling reactions.
• Ligand and Catalyst Development: Employed in the research and production of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Serves as a monomer or modifier in the development of advanced polymers with specific thermal or solubility properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies and exploring new chemical spaces in medicinal and synthetic chemistry laboratories.

Basic Information

Product Name	4-(Methylsulfonyl)Cyclohexanone
CAS No.	862129-72-4
Molecular Formula	C7H12O3S
Molecular Weight	176.23 g/mol
Synonyms	4-(Methanesulfonyl)cyclohexanone; 4-Methylsulfonylcyclohexanone; Cyclohexanone, 4-(methylsulfonyl)-; 4-Mesylcyclohexanone; 4-(Methylsulphonyl)cyclohexanone; 4-(Methylsulfonyl)cyclohexan-1-one; p-(Methylsulfonyl)cyclohexanone
EINECS	Contact for details

Quality Control

Our production of 4-(Methylsulfonyl)Cyclohexanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality system is designed to meet the rigorous standards required for cGMP and advanced R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.