Description

(R)-n-(But-3-En-2-Yl)Pyridine-2-Sulfonamide CAS NO 861848-44-4 is a high-purity, chiral sulfonamide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functional group compatibility, enabling the construction of complex molecules with precise spatial orientation. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric catalysis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological or metabolic diseases.
• Asymmetric Catalyst Ligand Precursor: Used in the synthesis of novel ligands for transition metal catalysts, enabling enantioselective transformations in fine chemical production.
• Agrochemical Research: Employed as a building block for developing new chiral herbicides, fungicides, or plant growth regulators with improved efficacy and environmental profiles.
• Medicinal Chemistry Probe: Utilized in structure-activity relationship (SAR) studies to explore the impact of the sulfonamide moiety and chiral center on biological activity.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material or intermediate for custom synthesis projects requiring specific chiral fidelity.
• Academic & Institutional Research: Used in university and institutional labs for methodological development in organic synthesis and stereochemistry.

Basic Information

Product Name	(R)-n-(But-3-En-2-Yl)Pyridine-2-Sulfonamide
CAS No.	861848-44-4
Molecular Formula	C9H12N2O2S
Molecular Weight	212.27 g/mol
Synonyms	(R)-N-(But-3-en-2-yl)pyridine-2-sulfonamide; (R)-N-(1-Methylallyl)pyridine-2-sulfonamide; (R)-N-(But-3-en-2-yl)-2-pyridinesulfonamide; 2-Pyridinesulfonamide, N-(1-methyl-2-propen-1-yl)-, (R)-; (R)-N-(1-Methyl-2-propenyl)-2-pyridinesulfonamide; (R)-N-(But-3-en-2-yl)picolinamide (common misnomer); (R)-2-Pyridylsulfonylbut-3-en-2-amine
EINECS	Contact for details

Quality Control

Our (R)-n-(But-3-En-2-Yl)Pyridine-2-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity (HPLC), chiral excess, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical R&D work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.