Description

n-[(1R,2R)-2-Aminocyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea is a high-purity, chiral thiourea derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a sophisticated organocatalyst and a key intermediate for developing novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and chemical manufacturers engaged in asymmetric synthesis, medicinal chemistry, and the development of high-value specialty chemicals.

Application

• Asymmetric Organocatalysis: Acts as a chiral hydrogen-bond donor catalyst for enantioselective synthesis, including Michael additions and other C-C bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a critical building block in the research and development of new drug candidates, particularly for chiral molecules.
• Ligand Synthesis: Used in the preparation of specialized ligands for metal-complex catalysis.
• Chemical Research: Employed in academic and industrial R&D for studying reaction mechanisms and developing new synthetic methodologies.
• Material Science Precursor: Potential use in creating advanced organic materials with specific electronic or structural properties.

Basic Information

Product Name	n-[(1R,2R)-2-Aminocyclohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea
CAS No.	860994-58-7
Molecular Formula	C15H17F6N3S
Molecular Weight	385.37 g/mol
Synonyms	(1R,2R)-N-[3,5-Bis(trifluoromethyl)phenyl]-N'-(2-aminocyclohexyl)thiourea; (1R,2R)-2-Amino-N-(3,5-bis(trifluoromethyl)phenyl)carbamothioylcyclohexan-1-amine; (1R,2R)-1-Amino-2-[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]aminocyclohexane; Chiral Thiourea Catalyst; (R,R)-Thiourea Organocatalyst; (1R,2R)-2-Amino-N-(3,5-bis(trifluoromethyl)phenyl)carbamimidothioic acid cyclohexane; 860994-58-7
EINECS	Contact for details

Quality Control

Our production of n-[(1R,2R)-2-Aminocychohexyl]-N'-[3,5-Bis(Trifluoromethyl)Phenyl]-Thiourea adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and identification data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.