Description

(R)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Piperazin-1-Yl-Methanone CAS NO 860173-98-4 is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic utility. This compound matters for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by pharmaceutical R&D laboratories, custom synthesis providers, and advanced fine chemical manufacturers seeking to develop enantiomerically pure drug candidates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential therapeutic agents, especially for neurological and psychiatric disorders.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Asymmetric Synthesis: Used in the development of novel catalytic and stoichiometric asymmetric methodologies due to its defined stereochemistry.
• Reference Standard: Employed as an analytical standard in quality control and method development for related pharmaceutical processes.
• Ligand Synthesis: Potential precursor for the synthesis of chiral ligands used in catalysis.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic and medicinal chemistry.

Basic Information

Item	Detail
Product Name	(R)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Piperazin-1-Yl-Methanone
CAS No.	860173-98-4
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	(R)-2-(Piperazine-1-carbonyl)-2,3-dihydrobenzo[b][1,4]dioxine; (R)-2-(Piperazine-1-carbonyl)chromane; (R)-2,3-Dihydro-1,4-benzodioxin-2-yl(piperazin-1-yl)methanone; (R)-2-(Piperazine-1-carbonyl)-2,3-dihydro-1,4-benzodioxin; (R)-1-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazine; (R)-1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylcarbonyl)piperazine; (R)-860173-98-4
EINECS	Contact for details

Quality Control

Our (R)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Piperazin-1-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.