Description

2-(4-Chlorophenyl)-2-Oxoacetaldehyde Hydrate is a versatile and reactive organic building block characterized by its chlorophenyl and highly electrophilic α-keto aldehyde functional groups. This compound matters as a critical synthetic intermediate, enabling the construction of complex heterocyclic and pharmaceutical scaffolds through its reactive carbonyl centers. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates, particularly those containing heterocyclic structures like imidazoles, pyrazoles, and quinoxalines.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the chlorophenyl moiety.
• Fine Chemical Production: Serves as a building block for dyes, pigments, and advanced organic materials requiring specific aromatic-aldehyde coupling.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new organic reactions and creating compound libraries for screening.
• Ligand and Catalyst Preparation: Useful in the synthesis of specialized ligands for metal catalysis or as a substrate in catalytic reaction studies.

Basic Information

Product Name	2-(4-Chlorophenyl)-2-Oxoacetaldehyde Hydrate
CAS No.	859932-64-2
Molecular Formula	C8H7ClO3 • xH2O
Molecular Weight	186.59 (Anhydrous basis)
Synonyms	2-(4-Chlorophenyl)-2-oxoacetaldehyde monohydrate; 4-Chlorophenylglyoxal hydrate; (4-Chlorophenyl)oxoacetaldehyde hydrate; α-Oxo-4-chlorobenzeneacetaldehyde hydrate; 2-Oxo-2-(4-chlorophenyl)ethanal hydrate; p-Chlorophenylglyoxal hydrate; 859932-64-2; 4-Chloro-α-oxobenzeneacetaldehyde hydrate
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-2-Oxoacetaldehyde Hydrate is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and water content. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply and traceability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) and minimize exposure to air and moisture during handling. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.