Description

4-Hexynoic Acid, 2-Amino-, Hydrochloride (1:1) is a specialized amino acid derivative featuring both an alkyne and a carboxylic acid functional group, making it a valuable chiral building block for advanced synthesis. This compound is crucial for researchers and manufacturers requiring precise molecular scaffolds to construct complex bioactive molecules. It is primarily utilized in pharmaceutical R&D for the synthesis of novel drug candidates, particularly in medicinal chemistry and peptide mimetics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the construction of peptide backbone modifications.
• Bioconjugation & Probe Development: The alkyne group enables click chemistry reactions for labeling biomolecules or creating diagnostic probes.
• Organic Synthesis: Acts as a versatile building block for synthesizing complex natural product analogs and heterocyclic compounds.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents with specific modes of action.
• Material Science: Potential monomer or cross-linker for creating functional polymers with tailored properties.

Basic Information

Product Name	4-Hexynoic Acid, 2-Amino-, Hydrochloride (1:1)
CAS No.	859842-08-3
Molecular Formula	C6H9NO2 • HCl
Molecular Weight	179.60 g/mol
Synonyms	2-Amino-4-hexynoic acid hydrochloride; 4-Hexynoic acid, 2-amino-, hydrochloride; 2-Aminohex-4-ynoic acid hydrochloride; (R/S)-2-Amino-4-hexynoic acid hydrochloride; Ethynylglycine derivative hydrochloride; Propargylglycine analog hydrochloride; Amino alkyne acid hydrochloride salt
EINECS	Contact for details

Quality Control

Our 4-Hexynoic Acid, 2-Amino-, Hydrochloride (1:1) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available upon request to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry, inert conditions to maintain product integrity and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.