Description

(6-Fluoro-4H-1,3-Benzodioxin-8-Yl)Methylamine Hydrochloride is a high-purity, fluorinated benzodioxin derivative supplied as a hydrochloride salt. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel active molecules. It is essential for researchers and manufacturers in medicinal chemistry and process development who require reliable, high-quality building blocks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development and optimization of scalable synthetic routes under GMP conditions.
• Agrochemical Research: Potential intermediate for the development of new crop protection agents and herbicides.
• Material Science: Can be utilized in the synthesis of advanced organic materials and ligands for catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.

Basic Information

Product Name	(6-Fluoro-4H-1,3-Benzodioxin-8-Yl)Methylamine Hydrochloride
CAS No.	859833-12-8
Molecular Formula	C9H9FNO2·HCl
Molecular Weight	215.63 (Free base) / 252.09 (HCl salt)
Synonyms	8-(Aminomethyl)-6-fluoro-4H-1,3-benzodioxin hydrochloride; 6-Fluoro-8-(aminomethyl)-4H-1,3-benzodioxin hydrochloride; (6-Fluoro-1,3-benzodioxin-8-yl)methanamine hydrochloride; 1-(6-Fluoro-4H-1,3-benzodioxin-8-yl)methanamine hydrochloride; 859833-12-8; (6-Fluoro-4H-benzo[d][1,3]dioxin-8-yl)methanamine hydrochloride
EINECS	Contact for details

Quality Control

Our (6-Fluoro-4H-1,3-Benzodioxin-8-Yl)Methylamine Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided and available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Anhydrous basis)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤3.0%; Any single impurity ≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.