Description

6-(Chloromethyl)-4-(3-Methoxypropyl)-2H-Benzo[B][1,4]Oxazin-3(4H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique benzo[b][1,4]oxazin-3(4H)-one core structure. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile reactive site for further chemical elaboration. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a versatile scaffold for the design and development of new chemical entities with potential biological activity.
• Process Development & Scale-up: Employed in optimizing synthetic routes for the cost-effective and scalable production of target compounds.
• Agrochemical Synthesis: Can be utilized as an intermediate in the research and development of novel crop protection agents.
• Material Science: Potential building block for the synthesis of specialty polymers or functional organic materials.

Basic Information

Product Name	6-(Chloromethyl)-4-(3-Methoxypropyl)-2H-Benzo[B][1,4]Oxazin-3(4H)-One
CAS No.	857272-02-7
Molecular Formula	C13H16ClNO3
Molecular Weight	269.73 g/mol
Synonyms	6-(Chloromethyl)-4-(3-methoxypropyl)-4H-benzo[b][1,4]oxazin-3-one; 4-(3-Methoxypropyl)-6-(chloromethyl)-2H-1,4-benzoxazin-3(4H)-one; 6-(Chloromethyl)-4-(3-methoxypropyl)-2H-1,4-benzoxazin-3(4H)-one; CAS 857272-02-7; Benzo[b][1,4]oxazin-3(4H)-one, 6-(chloromethyl)-4-(3-methoxypropyl)-; 6-Chloromethyl-4-(3-methoxypropyl)-2H-benzo[b][1,4]oxazin-3(4H)-one
EINECS	Contact for details

Quality Control

Our 6-(Chloromethyl)-4-(3-Methoxypropyl)-2H-Benzo[B][1,4]Oxazin-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (HPLC), related substances, and physical characteristics. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.